Claude 在 Claude Science 中自主设计出 17 个结合蝎毒的分子
Claude 作为智能体在 Anthropic 的 Claude Science 环境中自主完成蛋白设计流程：自行选定蝎毒靶点、驱动 12 个蛋白设计程序、设定打分阈值，从生成的 318,484 个分子中选出 180 个进行物理合成，最终 211 个设计中有 17 个在 Adaptyv Bio 和 Twist Bioscience 实验室测试中结合了对应毒素。
Claude did the protein scientist’s job and came back with 17 molecules that grip scorpion neurotoxins.
Claude, running as an agent inside Anthropic’s Claude Science setup, ran the whole protein-design campaign itself:
it picked which patch of each scorpion toxin to attack, drove 12 protein-design programs, set its own scoring cutoffs, and chose 180 molecules out of the 318,484 it generated for physical synthesis, and 17 of the 211 designs tested bound their toxin at Adaptyv Bio and Twist Bioscience.
Citrini Research, a finance firm with no lab and no protein expertise, asked for this work, and Claude designed proteins that two labs confirmed latch onto scorpion venom toxins.
Scorpion stings kill more than 3,250 people a year, so the prize is real, if this method works. However, Anthropic is not calling this an antivenom, because the test that would justify the word has not been run yet.
来源：rohanpaul_ai · x.com